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CHELATION THERAPY

Chelation therapy is a process involving the use of chelating agents to remove heavy metals from the body

Chelation Therapy uses a chelating agent such as EDTA or DMSA to tightly bind to heavy metals and transport them out of the body, generally through the urine. Oral Chelation is Chelation Therapy with the chelating agent administered orally. It was first developed as a method of treating heavy metal poisoning. Metals toxic to the human physiology include Lead, mercury, cadmium, arsenic and aluminum. It was later used by some physicians to treat atherosclerosis and coronary artery disease. It appears to be generally effective and generally safe. It fell into medical political disfavor apparently because it was relatively inexpensive and threatened vested financial interests. It has continued to be used by some physicians as a medically accepted but unapproved therapy.

The administration of chelating agents can be by mouth (orally), by intravenous drip, or by injection depending on the chelating agent and therapeutic goal.

The principal chelating agent used for these applications is the amino acid EDTA (ethylenediaminetetraacetic acid). Clinical Benefits of EDTA have been documented to include improved circulation, lowered cholesterol and blood lipids, lowered blood pressure, and an enhancement of energy production in the mitochondria. EDTA is considered by some to have life extension benefits. These benefits are believed to be due to the removal of heavy metals from the body. EDTA is also an anti-coagulant.

Examples of chelating agents
The choice of chelating agent depends on which metal is involved. Common chelating agents include:

  • Dimercaptosuccinic acid (DMSA)

  • Dimercapto-propane sulfonate (DMPS)

  • Alpha lipoic acid (ALA)

  • Calcium disodium versante (CaNa2-EDTA)

  • D-penicillamine

  • Deferoxamine

  • Defarasirox

  • Dimercaprol (BAL)

DMSA is Meso-2,3-dimercaptosuccinic acid, a sulfhydryl-containing compound that binds to metallic elements within the blood and helps balance metal factors in the body. DMSA is a potent chelator of mercury, Lead, arsenic and cadmium. This water-soluble, non-toxic, orally-administered substance has been in use as an antidote for heavy metal toxicity since the 1950s. However, recent clinical use substantiates DMSA's effectiveness and overall safety as one of the premier metal chelation compounds. Note: DMSA is useful for removing heavy metals but has not been proven to be effective in reversing atherosclerosis. Studies have shown that EDTA and DMSA taken together are more effective in removing heavy metals than either alone. Vitamin C is also a synergist in the removal of heavy metals. The amino acid Cysteine has anti-oxidant properties and helps to protect the liver and brain from heavy metal and free radical toxicity during chelation therapy.

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